Best Topicals Dispensaries in DeSoto County, MS (2026)

Location: 608 North Gloster Street, Tupelo

Location: 1223 Bienville Boulevard, Ocean Springs

Phone: (228) 215-3610

Location: 3016 Highway 51 South, Hernando

Phone: (662) 469-4046

Location: 409 Norfleet Drive, Senatobia

Phone: (662) 301-8657

Location: 2348 Mount Pleasant Road, Hernando

Phone: (662) 912-9048

Location: 2981 Harrah's Parkway South Extended, Tunica Resorts

Phone: (662) 373-4298

6 dispensaries carry topicals in DeSoto County, Mississippi, with an average rating of 4.8★ across 595 Google reviews. Mississippi is medical-only, so a state-issued medical cannabis card is required.

These dispensaries are concentrated in Tupelo, Ocean Springs and Hernando.

Which dispensaries are best for topicals in DeSoto County, Mississippi?

Top three by combined rating and review volume: Cannabis Headquarters, Rootdown and Herbal Alchemy LLC. Full ranking with addresses and hours is above.

How many dispensaries carry topicals?

6 licensed dispensaries in DeSoto County, Mississippi carry topicals.

Do I need a medical card to purchase topicals in Mississippi?

Yes. Mississippi only operates medical dispensaries; a state-issued card is required.

How much can I buy per visit in Mississippi?

Per-transaction limit: 3.5 grams per day, up to 3 ounces per month.

Best Topicals Dispensaries in DeSoto County, Mississippi (2026)

Cannabis Headquarters

Rootdown

Herbal Alchemy LLC

Five Star Medical Dispensary

Wyze Cannabis Dispensary

Lift Medical Cannabis

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Topicals Dispensaries in DeSoto County, Mississippi

Frequently Asked Questions about Topicals in DeSoto County, Mississippi

Which dispensaries are best for topicals in DeSoto County, Mississippi?

How many dispensaries carry topicals?

Do I need a medical card to purchase topicals in Mississippi?

How much can I buy per visit in Mississippi?