Best Dispensaries in Sioux Falls, SD (2026)

Sioux Falls has 6 active dispensaries, located in Davison and Brown counties. South Dakota is medical-only — purchases require a state-issued medical cannabis card.

Top three by rating + review volume: Genesis Farms Cannabis Dispensary, Flower Shop Dispensary and Roy'zzz Premium Cannabis.

Frequently Asked Questions about Sioux Falls Dispensaries

What are the best dispensaries in Sioux Falls?

Based on Google ratings, review volume, and user signals, the top three in Sioux Falls are Genesis Farms Cannabis Dispensary, Flower Shop Dispensary and Roy'zzz Premium Cannabis. See the full ranking above with addresses, hours, and links.

How many dispensaries operate in Sioux Falls?

6 licensed dispensaries are currently active in Sioux Falls, SD.

Do I need a medical card to buy cannabis in Sioux Falls?

Yes. South Dakota only operates medical dispensaries, so a state-issued medical cannabis card and a qualifying condition are required.

How much can I buy per visit in Sioux Falls?

Per-transaction limit set by South Dakota: 3 ounces per 14-day period.